DHA and EPA are further metabolized in our body to series 3 prostaglandins (PGE3), which are extremely active hormone-like substances. These prostaglandins are very important for proper brain function, affecting vision, learning ability, co-ordination and mood. They help to reduce the thickening of blood, control blood cholesterol and fat levels, improve immune function and metabolism, reduce inflammation and maintain water balance in our body. Many studies had confirmed that a balanced formulation of DHA and EPA taken daily is as effect in controlling inflammation, such as rhematoid arthritis, as the conventional pharmaceuticals under the Non Steroid Anti-inflammatory Drugs.

Symptoms of deficiency of this important fat include dry skin, inflammatory health problems (e.g. joints & muscles aches), water retention, tingling in the arms or legs, high blood pressure or high in bad cholesterol, infections, poor memory and learning problems, lack of co-ordination, poor vision and retarded growth in children. The best food source of Omega 3 fats are from fish and flax seeds. A supplement of 600 mg of Omega 3 from tuna fish oil will be able to meet with the daily needs.

Fish and fish oils provide a powerful natural source of Omega 3 fats, EPA and DHA. Eating fish or their oils will by pass the first two steps of conversion stage of alpha-linolenic acid as illustrated in the above diagram, to provide DHA and EPA. For this reason, fish eaters like the Japanese and Eskimos seem to have lower incidences of heart problems, and longer life. Unfortunately, most oceans and consequently the fish in the world are polluted with industrial chemicals. Japan Government exercise great precaution to ensure the water in their seas are not contaminated as their people's diet is rich in fish.